The benefits of early diagnosis

At York Instruments, we believe everyone affected by epilepsy deserves to live life to the fullest. As part of our core mission to enhance early diagnosis methods, we are working towards allowing everyone affected by epilepsy to live a life as free from seizures as possible. We set out to make a difference to every person and family affected by epilepsy whatever their background, however seriously it affects them.

A powerful tool for epilepsy clinicians

Magnetoencephalography (MEG) is a valuable tool for characterizing and localizing epileptic activity, as well as localizing brain function. The scans are non-invasive, virtually silent and well-tolerated by patients of all ages, including young children.

Use of MEG leads to improved surgical outcomes. Why? It provides a direct measure of electrophysiology, and the patient data is not distorted by skull and scalp. Clinicians appreciate the accuracy of MEG scans which offer temporal and spatial accuracy—to the millisecond and millimeter.

MEGSCAN is for investigational use only. It is not available for clinical use until regulatory approvals have been granted.

Benefits of MEGSCAN

MEGSCAN from York Instruments combines advances in electronics, software, cryogenics and magnetic sensors in a robust, extensible MEG system with vastly improved signal-to-noise.

  • 320 magnetic sensors, each located at an independent position over the scalp. This means a larger number of sensor channels than any system currently on the market.
  • MEGSCAN’s sensors are cooled using a heat extraction system. This removes the need for costly supplies of liquid helium, and for regular user maintenance.
  • Exquisite sensitivity, along with ultra-low environmental interference, is achieved by combining advanced electronics, state-of-the-art HyQUID sensors and an extensive reference array.
  • A suite of powerful, easy-to-use data acquisition and data viewing tools.

MEG as a diagnostic tool: a comparison

fMRI vs MEG

fMRI is used to localise brain functions prior to surgery. This offers an indirect measure of brain activity with poor temporal resolution.

MEG offers excellent temporal and spatial resolution.  The scan data is a direct measure of electrophysiological activity within the brain and therefore more accurate.

EEG vs MEG

Long-term monitoring EEG requires large numbers of electrodes to be consistently positioned on the subject’s head. Spike localization accuracy is poor due to the conduction of the signal through the skull and the scalp.

Greater accuracy of source localization is possible with MEG as the skull and scalp are transparent to the magnetic signals, allowing a consistent, clean data signal. Temporal history and the migration of activity from site to site can be monitored with MEG. MEGSCAN™ offers easy synchronous MEG/EEG data capture in partnership with ANT Neuro.

SPECT vs MEG

SPECT is highly invasive: it requires a contrast medium to be injected, and preferably, for the subject to be having an epileptic event.

MEG is non-invasive: the patient experience is peaceful and comfortable. There is no need to inject patients or require them to undergo epileptic events. Many patients fall asleep during their MEG scan.

ECoG vs MEG

ECoG is used for interoperative epilepsy localization during surgery. It is an effective feedback method to quickly identify eloquent areas, but is highly invasive. ECoG cannot be used for all brain areas due to difficulty of access.

MEG does not require the invasive placing of electrode strips over brain areas. Virtual electrodes can be used to monitor all brain areas.

Going in for a MEG scan?

Having a MEG scan is quiet and non-invasive. Learn more about what you can expect.